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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
24.24
Human Site:
Y1101
Identified Species:
38.1
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
Y1101
P
K
P
I
E
Y
E
Y
I
N
S
Q
G
S
E
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
Y1101
P
K
P
I
E
Y
E
Y
I
N
S
Q
G
S
E
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
S781
T
Q
L
C
D
W
W
S
V
G
V
I
L
F
E
Dog
Lupus familis
XP_534537
1097
121903
P1067
Y
P
F
R
C
P
K
P
S
G
A
D
A
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
Y1100
P
K
P
I
E
Y
E
Y
I
H
S
Q
G
S
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
Y1091
P
K
P
I
E
Y
E
Y
S
S
S
Q
N
S
E
Chicken
Gallus gallus
XP_419666
1136
127431
Y1107
P
K
P
I
E
Y
E
Y
S
S
S
Q
N
S
E
Frog
Xenopus laevis
NP_001087838
1118
125984
Y1087
P
K
P
F
R
Y
D
Y
D
D
S
Q
D
T
G
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
S1039
S
C
P
K
P
I
E
S
E
E
E
D
E
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
H1077
D
Q
N
D
R
T
F
H
G
F
F
E
F
T
F
Honey Bee
Apis mellifera
XP_395146
1137
124999
R1109
G
F
F
E
F
T
F
R
R
F
F
D
D
G
G
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
L448
T
Y
K
R
F
D
G
L
T
Q
K
M
R
Y
S
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
S1170
P
M
P
I
D
I
D
S
S
P
G
P
G
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
G728
R
E
Q
M
T
K
Q
G
G
S
A
P
V
K
E
Red Bread Mold
Neurospora crassa
P38679
598
67999
A570
Q
Q
A
A
R
G
A
A
A
P
A
Q
Q
E
E
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
6.6
6.6
N.A.
93.3
N.A.
N.A.
80
80
46.6
20
N.A.
0
0
0
26.6
P-Site Similarity:
100
100
33.3
26.6
N.A.
100
N.A.
N.A.
86.6
86.6
66.6
20
N.A.
26.6
0
0
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
0
7
7
7
0
20
0
7
0
0
% A
% Cys:
0
7
0
7
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
14
7
14
0
7
7
0
20
14
7
0
% D
% Glu:
0
7
0
7
34
0
40
0
7
7
7
7
7
14
60
% E
% Phe:
0
7
14
7
14
0
14
0
0
14
14
0
7
7
7
% F
% Gly:
7
0
0
0
0
7
7
7
14
14
7
0
27
7
14
% G
% His:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
40
0
14
0
0
20
0
0
7
0
0
0
% I
% Lys:
0
40
7
7
0
7
7
0
0
0
7
0
0
7
0
% K
% Leu:
0
0
7
0
0
0
0
7
0
0
0
0
7
0
0
% L
% Met:
0
7
0
7
0
0
0
0
0
0
0
7
0
0
7
% M
% Asn:
0
0
7
0
0
0
0
0
0
14
0
0
14
0
0
% N
% Pro:
47
7
54
0
7
7
0
7
0
14
0
14
0
0
0
% P
% Gln:
7
20
7
0
0
0
7
0
0
7
0
47
7
0
7
% Q
% Arg:
7
0
0
14
20
0
0
7
7
0
0
0
7
0
0
% R
% Ser:
7
0
0
0
0
0
0
20
27
20
40
0
0
40
7
% S
% Thr:
14
0
0
0
7
14
0
0
7
0
0
0
0
14
0
% T
% Val:
0
0
0
0
0
0
0
0
7
0
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
0
40
0
40
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _